Discrepancy between Vitamin D Total Immunoassays due to Various Cross-reactivities
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چکیده
منابع مشابه
Discrepancy between Vitamin D Total Immunoassays due to Various Cross-reactivities
BACKGROUND The purpose of this study was to find out the cause of discrepancy between various automated immunoassays for 25-hydroxy-vitamin D (25-[OH]D). METHODS National Institute of Standards & Technology Standard Reference Material (SRM) 972a is SRM for 25-(OH)D and consists of 4 vials of frozen serum with different concentrations of 25-(OH)D. Each concentration was measured 6 times in 3 d...
متن کاملHypercalcemic crisis due to vitamin D toxicity.
1. What should be included in the differential diagnosis of hypercalcemia? Are the patient’s laboratory findings consistent with her reported use of vitamin supplements? 2. What role does vitamin D play in Ca2+ homeostasis? 3. Other than excess nutritional supplement use, what are additional causes of vitamin D toxicity? 4. What are the symptoms of vitamin D toxicity? How should vitamin D toxic...
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Introduction: Vitamin D is increasingly recognized as playing a significant role in combatting many diseases. One is the development of secondary hyperthyroidism due vitamin D deficiency. To date, laboratory quantification methods of serum vitamin D were not well standardized. It could not be established with certainty from which levels of vitamin D certains abnormalities take place, like an el...
متن کاملMulticenter Comparison of Seven 25OH Vitamin D Automated Immunoassays
BACKGROUND The measurement of 25OH vitamin D continues to grow in clinical laboratories. The aim of this multi-center study was to compare the results of seven automated commercial immunoassays with a reference HPLC technique. METHODS One hundred and twenty consecutive outpatient serum samples were centrifuged, divided in aliquots, frozen and shipped to the participating laboratories. 25OH Vi...
متن کاملvitamin d intoxication with hypercalcemia due to overuse of supplement
we describe a patient with hypercalcemia associated with the injection of high doses vitamin d as supplement for a period of six months. a 76-year-old woman had been taking an intramuscular injection of vitamin d 300,000 iu every ten days for six months. she was hospitalized with symptoms of hypercalcemia: chronic constipation, unstable gait, a chronic generalized musculoskeletal pain and incre...
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ژورنال
عنوان ژورنال: Journal of Bone Metabolism
سال: 2015
ISSN: 2287-6375,2287-7029
DOI: 10.11005/jbm.2015.22.3.107